Biotech

Kit de sondas de detección de LA
deleción 7q (brazo largo del cromosoma 7)

7q chromosome deletion detection probe kit

Deletion of the entire chromosome 7 or deletion of the long arm 7q is a recurrent abnormality in MDS, and its incidence is about 15% in patients with MDS.

Probe description

7q chromosome deletion probe labels the 7q22 region with an orange-red dye and the D7S486 region with a green dye.

Clinical significance  

Patients with 7q-deficient have a MDS poor prognosis and are prone to infection and conversion to white blood cells (leukocytes).

References

  • Coleman JF, et al. (2011) Am J Clin Pathol 135: 915-20.
  • Kawankar N, et al. (2010) Hematology, 16:131-8. 

 

Product size: 100μL FISH probe ( |  ) + Pretreatment reagent (10 tests) + Antifade staining solution DAPI (10 tests).